I’m starting a new project. Sometimes it takes a lot of time, before I can publish a new video. That doesn’t mean I’m doing nothing. From now on, I’ll publish new findings and conclusions here. <\/p>\n\n\n\n
In my last video I explained why I think that ER stress (endoplasmic reticulum stress) is (part of) the cause for ME\/CFS. ER stress refers to a disturbance of a cell’s metabolism that is caused by protein misfolding. Protein misfolding always happens, so it’s not necessarily a problem. But a number of factors can make this problem so much worse that several processes of a cell’s metabolism may be disrupted. Examples for such factors are viral infections and genetic mutations. Causes of ER stress, from my experience with Fabry disease, are brain fog, exhaustion and inflammation. Additional problems may arise when cells start dying because of ER stress. Even though this connection is not proven, I consider ER stress to be a likely cause for small fibre neuropathy. The video, which includes many scientific sources, can be found here: <\/p>\n\n\n\n